WHAT DOES CHOLESTEROL HAVE TO DO WITH HEART DISEASE?

Many international studies have shown that a high level of cholesterol in the blood increases the risk of developing CHD. Cholesterol is a waxy, fat-like substance that occurs naturally in cells everywhere in the body. Your body uses cholesterol to make cell membranes, hormones, vitamin D, and bile acids which are needed for the digestion [...]

Women and Heart Disease

When you think of diseases that affect women, what do you think of? Do you think ofheart disease? Well, you should! Heart disease is not just a man’s disease. Heart attack, stroke and other cardiovascular diseases are devastating to women, too. Infact, coronary heart disease, which causes heart attacks, is the number ONE cause of [...]

Cholesterol and coronary heart disease: screening and treatment

Despite the declining coronary heart disease(CHD) mortality rate, CHD remains a major cause of premature death and imposes high personal,social and economic costs. s Blood cholesterol is an important risk factor for CHD but should be considered in the context of other risk factors such as smoking, raised blood pressure and physical in activity. s [...]

Transforming Growth Factor -?, Cell Signaling and Cardiovascular Disorders

Abstract: Transforming growth factor-beta (TGF-?) is a multifunctional growth factor with a wide range of potential effects on growth, differentiation, extracellular matrix accumulation and the immune system. It has been implicated in many cardiovascular disorders. TGF-?’s actions are mediated via a complex between its type I and type II receptors resulting in the phosphorylation of [...]

Cholesterol and Lipoproteins

CHOLESTEROL Cholesterol is essential for life and present throughout thebody. It is abundant in the brain, nervous tissue, skin andadrenal glands. Production and function Cholesterol has three principal functions within the body. Itis a structural component of all cell membranes; is used tomanufacture steroid hormones and Vitamin D; and is usedto produce bile acids, which [...]

BMC Cardiovascular Disorders

Abstract Background: The occurrence of variations in the spectrum of cardiovascular disease betweendifferent regions of the world and ethnic groups have been the subject of great interest. This studyreport the 24-h variation of myocardial infarction (MI) occurrence in patients recruited from CCUlocated in Argentina and Uruguay.Methods: A cohort of 1063 patients admitted to the CCU [...]

Modeling an Avian-Human Hybrid Flu Virus

Influenza A Virus Viral RNA Viral Core N Glycoprotein H Glycoprotein Lipid Envelope Pandemic Influenza Viewing Activity Teacher Notes Influenza A infects humans and animals such as birds, pigs, horses, and seals. When it infects birds, it is called avian influenza; when it infects pigs, it is called swine influenza, and so on. Typically, avian [...]

Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease

Celiac disease, also known as celiac sprue, is a gluten-inducedautoimmune-like disorder of the small intestine, which is stronglyassociated with HLA-DQ2. The structure of DQ2 complexed with animmunogenic epitope from gluten, QLQPFPQPELPY, has been de-termined to 2.2-Å resolution by x-ray crystallography. The gluta-mate at P6, which is formed by tissue transglutaminase-catalyzeddeamidation, is an important anchor residue [...]

Information about Avian Influenza (Bird Flu) and Avian Influenza A (H5N1) Virus

This fact sheet provides general information about bird flu and information about one type of bird flu,called avian influenza A (H5N1) that is infecting birds in Asia and has infected some humans. Also see the Frequently Asked Questions (FAQs)(http://www.who.int/csr/disease/avian_influenza/avian_faqs/en/index.html) on the World Health Organization (WHO) website. Avian Influenza (Bird Flu)Avian influenza in birds Avian influenza [...]

Valacyclovir for Herpes Simplex Virus Infection

An extensive clinical trial program combined with 5 years’ postmarketing experience withvalacyclovir provides evidence of favorable safety and efficacy in herpes simplex virus (HSV)management. Valacyclovir enhances acyclovir bioavailability compared with orally adminis-tered acyclovir. Long-term use of acyclovir for up to 10 years for HSV suppression is effectiveand well tolerated. Acyclovir is also approved for use [...]